Bettencourt M J
Laboratório Moniz de Bettencourt, Instituto de Fisiologia, Faculdade de Medicina de Lisboa.
Rev Port Cardiol. 1994 Jun;13(6):527-39, 477.
This paper studying diastolic left ventricular and myocardial elastic and viscoelastic properties, some of its consequences and its quantification, constitutes the fourth part of a review on circulatory system elasticity and viscoelasticity. The ventricular elastic and viscoelastic properties depend on myocardial ones and on chamber shape and dimensions. Thus it is often necessary to quantify the ventricular and the myocardial properties separately. As an approximation, the viscoelastic effects during diastole can be neglected and the elastic properties deduced from data obtained over the entire filling; however, these properties can be quantified rigorously only when using viscoelastic models. Another method of exact quantification is based on diastatic data alone; the latter do not reflect significant viscoelastic effects because they correspond to a period in which deformation rate is very slow. This study includes several Pathophysiological applications: some alterations in ventricular elastic properties induced by the pericardium are analysed and deviations from normal ventricular and myocardial diastolic properties caused by primary angina pectoris, by effort angina pectoris and by hypertrophy due to volume and pressure overload are examined. The basic Physical and Biophysical concepts essential to the better phenomena understanding are exposed in the first part of this work which constitutes a previous paper component.
本文研究左心室舒张期的弹性和粘弹性特性、其一些后果及其量化，构成了关于循环系统弹性和粘弹性综述的第四部分。心室的弹性和粘弹性特性取决于心肌特性以及腔室形状和尺寸。因此，通常需要分别量化心室和心肌的特性。作为一种近似方法，舒张期的粘弹性效应可以忽略不计，并根据整个充盈期获得的数据推导弹性特性；然而，只有在使用粘弹性模型时，这些特性才能得到严格量化。另一种精确量化的方法仅基于舒张期数据；后者不能反映显著的粘弹性效应，因为它们对应于变形速率非常缓慢的时期。本研究包括几个病理生理学应用：分析了心包引起的心室弹性特性的一些改变，并研究了原发性心绞痛、劳力性心绞痛以及容量和压力过载导致的肥大引起的心室和心肌舒张特性与正常情况的偏差。为了更好地理解这些现象所必需的基本物理和生物物理概念在构成本文前一篇论文组成部分的第一部分中进行了阐述。
