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一种伴有t(8;13) (p11;q12)的非典型骨髓增殖性疾病：第三例病例

An atypical myeloproliferative disorder with t(8;13) (p11;q12): a third case.

作者信息

Macdonald D, Sheerin S M, Cross N C, Spencer A, Goldman J M

机构信息

LRF Centre for Adult Leukaemia, Royal Postgraduate Medical School, Hammersmith Hospital, London.

出版信息

Br J Haematol. 1994 Apr;86(4):879-80. doi: 10.1111/j.1365-2141.1994.tb04848.x.

DOI:10.1111/j.1365-2141.1994.tb04848.x
PMID:7918089
Abstract

A 43-year-old male presented with a myeloproliferative disorder with prominent lymphadenopathy. Examination of the bone marrow showed almost complete replacement by a population of cells with an acquired chromosomal translocation t(8;13)(p11;q12). There are two other case reports describing a similar clinical syndrome with t(8;13)(p11;q12) as the sole chromosomal aberration in bone marrow cells, suggesting a role for this translocation in the pathogenesis of this myeloproliferative disorder.

摘要

一名43岁男性因骨髓增殖性疾病伴显著淋巴结肿大就诊。骨髓检查显示，一群获得性染色体易位t(8;13)(p11;q12)的细胞几乎完全替代了骨髓。另外还有两篇病例报告描述了类似的临床综合征，t(8;13)(p11;q12)是骨髓细胞中唯一的染色体畸变，提示这种易位在该骨髓增殖性疾病的发病机制中起作用。

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An atypical myeloproliferative disorder with t(8;13) (p11;q12): a third case.一种伴有t(8;13) (p11;q12)的非典型骨髓增殖性疾病：第三例病例
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引用本文的文献

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Myeloproliferative Syndrome With Eosinophilia Associated With Translocation t(8; 13) and T-cell Lymphoblastic Lymphoma: A Case Report and Review of the Literature.伴有嗜酸性粒细胞增多的骨髓增殖性综合征与t(8;13)易位及T细胞淋巴母细胞淋巴瘤相关：一例报告并文献复习
Cureus. 2022 Mar 1;14(3):e22734. doi: 10.7759/cureus.22734. eCollection 2022 Mar.
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The 8p11 myeloproliferative syndrome: review of literature and an illustrative case report.8p11骨髓增殖综合征：文献综述及一例病例报告
Int J Clin Exp Pathol. 2008 Jan 1;1(5):448-56.
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Induction of the plasminogen activator inhibitor-2 in cells expressing the ZNF198/FGFR1 fusion kinase that is involved in atypical myeloproliferative disease.
在表达与非典型骨髓增殖性疾病相关的ZNF198/FGFR1融合激酶的细胞中诱导纤溶酶原激活物抑制剂-2。
Blood. 2006 May 1;107(9):3693-9. doi: 10.1182/blood-2005-04-1505. Epub 2006 Jan 12.
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[The 8p11 myeloproliferative syndrome].[8p11骨髓增殖综合征]
Med Klin (Munich). 1999 Apr 15;94(4):207-10. doi: 10.1007/BF03044856.