Bailey A L, Finglas P M, Wright A J, Southon S
AFRC Institute of Food Research, Norwich Laboratory, Colney.
Br J Nutr. 1994 Jul;72(1):111-25. doi: 10.1079/bjn19940014.
The relationships between thiamin intake, erythrocyte transketolase (EC 2.2.1.1) activity coefficient (ETK-AC) and total erythrocyte thiamin were investigated in a group of adolescents (13 to 14 years old; nineteen boys, thirty-five girls). Thiamin intakes were calculated from 7 d weighed records, using food composition tables, and compared with those obtained by direct analysis of duplicate diets. Average 7 d calculated thiamin intakes were significantly lower than analysed intakes for both sexes. On an individual basis, calculated intakes ranged from 30 to 143% of corresponding analysed values. Analysed and calculated intakes were significantly correlated when expressed as mg/d; however, when expressed in terms of energy intake, the correlation was significant for males only. Thiamin intake appeared largely adequate when compared with current UK dietary recommendations (Department of Health, 1991), but the limitations of such comparisons are considered. The major food groups contributing to thiamin intake were examined and showed breakfast cereals to contribute more than 25% of dietary thiamin. A proportion of the subjects had ETK-AC values in ranges usually associated with marginal or severe thiamin deficiency. There was, however, no statistically significant relationship between erythrocyte thiamin and basal or stimulated transketolase activity, or between thiamin intake and either of the methods used to assess status. The need to re-evaluate indices of thiamin status is discussed.
对一组青少年（13至14岁；19名男孩，35名女孩）的硫胺素摄入量、红细胞转酮醇酶（EC 2.2.1.1）活性系数（ETK-AC）和红细胞总硫胺素之间的关系进行了研究。硫胺素摄入量根据7天称重记录，使用食物成分表计算得出，并与通过对重复饮食进行直接分析获得的摄入量进行比较。男女的平均7天计算硫胺素摄入量均显著低于分析摄入量。就个体而言，计算摄入量在相应分析值的30%至143%之间。以毫克/天表示时，分析摄入量与计算摄入量显著相关；然而，以能量摄入量表示时，仅男性的相关性显著。与英国当前的饮食建议（卫生部，1991年）相比，硫胺素摄入量似乎基本充足，但考虑了此类比较的局限性。对硫胺素摄入的主要食物类别进行了检查，结果显示早餐谷物贡献了超过25%的膳食硫胺素。一部分受试者的ETK-AC值处于通常与边缘性或严重硫胺素缺乏相关的范围内。然而，红细胞硫胺素与基础或刺激转酮醇酶活性之间，以及硫胺素摄入量与用于评估状态的任何一种方法之间均无统计学上的显著关系。讨论了重新评估硫胺素状态指标的必要性。
