Messaritakis J, Psychou F, Dracou C, Nicolaidou P, Kakourou T
1st Department of Paediatrics, Athens University, Children's Hospital, Greece.
Acta Paediatr. 1994 Jun;83(6):681-3. doi: 10.1111/j.1651-2227.1994.tb13114.x.
Arthritis and vasculitis are very rare complications of varicella occurring almost exclusively after the eruption of the characteristic rash. We report two children, aged three and seven years, who developed vasculitis and polyarthritis (patient No. 1) and arthritis (patient No. 2) 13 and 9 days, respectively, before the onset of their typical varicella. Arthritis and vasculitis so early in the incubation period of varicella have not been described previously. In all previously reported cases the arthritis occurred after or together with the onset of varicella and only in one instance preceded the exanthem by 2 days. Although this may have been an unfortunate coincidence, an association between varicella zoster virus and these manifestations should be seriously considered. Clinicians confronted with such cases must be cautious and search for varicella infection, especially in times of epidemics.
关节炎和血管炎是水痘非常罕见的并发症，几乎仅在特征性皮疹出现后发生。我们报告了两名儿童，年龄分别为3岁和7岁，他们分别在典型水痘发作前13天和9天出现了血管炎和多关节炎（1号患者）以及关节炎（2号患者）。水痘潜伏期如此早期出现的关节炎和血管炎此前尚未有过描述。在所有先前报道的病例中，关节炎在水痘发作后或同时出现，仅在1例中皮疹出现前两天出现。尽管这可能是不幸的巧合，但应认真考虑水痘带状疱疹病毒与这些表现之间的关联。面对此类病例的临床医生必须谨慎，并寻找水痘感染情况，尤其是在流行期间。
