Sasaki K, Kijima K, Kojima S
Eisei Shikenjo Hokoku. 1993(111):57-60.
Riboflavin (RF), flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) caused hemolysis of isolated rabbit erythrocytes by UVA-sensitization. Hemolysis induced by UVA-sensitization with RF and FMN was inhibited by 1.0 mM histidine and EDTA, and was promoted by 0.15 mM histidine and 0.01 mM NaN3. Hemolysis induced by irradiation in anaerobic condition was smaller than those in aerobic condition. Hemolysis was proceeded in the dark for 5 hours after the UVA-irradiation with RF and FAD. Erythrocyte treated by UVA-sensitization with RF easily caused hypotonic hemolysis.
核黄素（RF）、黄素单核苷酸（FMN）和黄素腺嘌呤二核苷酸（FAD）通过紫外线A（UVA）致敏作用导致离体兔红细胞溶血。1.0 mM组氨酸和乙二胺四乙酸（EDTA）可抑制由RF和FMN经UVA致敏诱导的溶血，而0.15 mM组氨酸和0.01 mM叠氮化钠可促进该溶血。在厌氧条件下照射诱导的溶血比在需氧条件下的溶血小。在用RF和FAD进行UVA照射后，溶血在黑暗中持续5小时。经RF进行UVA致敏处理的红细胞容易发生低渗溶血。
