Uimonen S, Laitakari K, Bloigu R, Reinilä M, Sorri M
Department of Otolaryngology, University of Oulu, Finland.
J Vestib Res. 1994 Jul-Aug;4(4):277-83.
Twelve health subjects were assessed using static posturography before and after intravenous alcohol infusion in a double-blind experiment. The dose was 0.5 g ethanol per kg body weight in 15 minutes, which raised the blood alcohol concentration to a level of approximately 1 mg/mL. Among other parameters, the average body sway velocity (BSV) and area of body sway (BSA) were measured. BSV was the most sensitive parameter for detecting increased body sway after alcohol infusion, and a significant effect of alcohol on its values was seen at 0.46 to 1.0 mg/mL alcohol concentrations. The second best indicator was the BSA. There was a positive correlation between the BSV and the BSA. The other parameters were not affected. The Romberg quotient remained constant during the alcohol test. The test battery used was relevant to distinguish the effect of alcohol on balance. In this study, acute blood alcohol concentrations of around 0.5 to 1.0 mg/mL affected BSV more significantly than BSA. The authors do not, however, recommend the test for forensic purposes in examining drivers with alcohol in their blood, as there is too much interindividual dispersion in the results.
在一项双盲实验中，对12名健康受试者在静脉输注酒精前后进行了静态姿势描记法评估。剂量为每公斤体重0.5克乙醇，在15分钟内输注完毕，这使血液酒精浓度升高至约1毫克/毫升。除其他参数外，还测量了平均身体摇摆速度（BSV）和身体摇摆面积（BSA）。BSV是检测酒精输注后身体摇摆增加的最敏感参数，在酒精浓度为0.46至1.0毫克/毫升时，可观察到酒精对其值有显著影响。第二好的指标是BSA。BSV和BSA之间存在正相关。其他参数未受影响。在酒精测试期间，罗姆伯格商数保持不变。所使用的测试组合有助于区分酒精对平衡的影响。在本研究中，急性血液酒精浓度约为0.5至1.0毫克/毫升时，对BSV的影响比对BSA的影响更显著。然而，作者不建议将该测试用于法医检查血液中含酒精的司机，因为结果存在太多个体差异。
