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磷矿石和磷灰石粉尘的体外溶血活性

Hemolytic activity of phosphorite and apatite dusts in vitro.

作者信息

Mikulski T, Mierzecki A, Przepiera A, Swiech Z

机构信息

Department of Hygiene, Pomeranian Medical Academy, Szczecin, Poland.

出版信息

Int J Occup Med Environ Health. 1994;7(1):59-64.

PMID:7921904
Abstract

An examination was performed to assess the hemolytic activity of phosphorite and apatite dust in vitro by a method used by Potts et al. (1978). After evaluation of dispersion, a certain contents of elements was established, using a spectrometer of X-ray fluorescence. Phosphorite dusts caused 50.4% of hemolyse that is about 5 times more than those caused by dust of apatites. The mean hemolysis index for phosphorite dust was 0.799 and for apatite dust 0.142. Thus, phosphorites are much more toxic to a human being than apatites. A higher level of hemolytical activity in phosphorite dust as compared to apatite one can be explained by significant difference in the contents of certain elements, SiO2, in particular. The mean SiO2 level in samples containing phosphorites was 6.3 +/- 0.1% compared to samples of apatites (3.8 +/- 0.09%).

摘要

采用Potts等人(1978年)使用的方法,进行了一项体外实验,以评估磷灰石和磷矿石粉尘的溶血活性。在评估分散度后,使用X射线荧光光谱仪确定了特定元素的含量。磷矿石粉尘引起了50.4%的溶血,这比磷灰石粉尘引起的溶血多约5倍。磷矿石粉尘的平均溶血指数为0.799,磷灰石粉尘的平均溶血指数为0.142。因此,磷矿石对人体的毒性比磷灰石大得多。与磷灰石粉尘相比,磷矿石粉尘中更高水平的溶血活性可以通过某些元素(特别是SiO2)含量的显著差异来解释。含磷矿石样品中的平均SiO2水平为6.3 +/- 0.1%,而磷灰石样品中的平均SiO2水平为3.8 +/- 0.09%。

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