利钠肽家族。
The natriuretic peptide family.
作者信息
Nakao K, Itoh H, Suga S, Ogawa Y, Imura H
机构信息
Department of Medicine, Kyoto University School of Medicine, Japan.
出版信息
Curr Opin Nephrol Hypertens. 1993 Jan;2(1):45-50. doi: 10.1097/00041552-199301000-00007.
The natriuretic peptide system is a complicated system comprising at least three endogenous peptides, atrial natriuretic peptide, brain natriuretic peptide, and C-type natriuretic peptide and three receptors, the atrial natriuretic peptide-A receptor (guanylyl cyclase A), the atrial natriuretic peptide-B receptor (guanylyl cyclase B), and the clearance receptor. The accumulated evidence indicates that this system is implicated in the control of blood pressure, body fluid homeostasis, and vascular remodeling as both cardiac hormone and local regulator.
利钠肽系统是一个复杂的系统，至少由三种内源性肽（心房利钠肽、脑利钠肽和C型利钠肽）以及三种受体（心房利钠肽-A受体（鸟苷酸环化酶A）、心房利钠肽-B受体（鸟苷酸环化酶B）和清除受体）组成。越来越多的证据表明，该系统作为心脏激素和局部调节因子，参与血压控制、体液平衡和血管重塑。
Zotero 插件