Pathobiology of focal sclerosis.
作者信息
Wolthuis A, van Goor H, Weening J J, Grond J
机构信息
Department of Pathology, University of Groningen, The Netherlands.
出版信息
Curr Opin Nephrol Hypertens. 1993 May;2(3):458-64. doi: 10.1097/00041552-199305000-00014.
Abstract
This paper briefly reviews recent experimental data derived from work in animals and cell cultures that have increased our understanding of the pathobiologic pathways leading to focal sclerosis. These pathways include glomerular visceral epithelial cell damage, leukocyte infiltration, hyperplasia and matrix accumulation in the mesangium, and endothelial injury.
摘要
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