转录激活。λ阻遏蛋白如何与RNA聚合酶进行交流。
Transcriptional activation. How lambda repressor talks to RNA polymerase.
作者信息
Hochschild A
机构信息
Department of Microbiology and Molecular Genetics, Harvard Medical School, Boston, Massachusetts 02115.
出版信息
Curr Biol. 1994 May 1;4(5):440-2. doi: 10.1016/s0960-9822(00)00097-x.
PMID:7922360
Abstract
The bacteriophage lambda repressor protein can activate or repress transcription. Amino-acid substitutions in the sigma subunit of RNA polymerase affect repressor-stimulated transcription, shedding light on the activation process.
摘要
噬菌体λ阻遏蛋白可激活或抑制转录。RNA聚合酶σ亚基中的氨基酸替换会影响阻遏蛋白刺激的转录，从而揭示激活过程。
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