Demling R H, Knox J B
Longwood Area Trauma/Burn Center, Brigham and Women's Hospital, Boston, MA.
New Horiz. 1993 Aug;1(3):362-70.
Acute respiratory failure is a complex disease process. However, it can be understood and appropriately managed if the key components of normal lung function are well understood and abnormalities are specifically identified. These components include oxygenation, ventilation, and respiratory mechanics. The abnormalities, which include hypoxia, hypercarbia, and altered compliance, can be present together or independent of each other. The optimum treatment modality will depend on which component predominates and on the factors producing changes from normal.
急性呼吸衰竭是一个复杂的疾病过程。然而，如果对正常肺功能的关键组成部分有充分的了解，并能明确识别异常情况，那么就可以理解并妥善处理该疾病。这些组成部分包括氧合、通气和呼吸力学。异常情况包括低氧血症、高碳酸血症和顺应性改变，它们可能同时出现，也可能相互独立。最佳的治疗方式将取决于哪个组成部分占主导地位，以及导致与正常情况产生差异的因素。
