Wang Y Y, George J, Shi Q
Shanxi Medical College, Taiyuan.
Zhonghua Yi Xue Za Zhi. 1994 Apr;74(4):211-3, 254.
Genomic DNAs isolated from 9 families and 13 unrelated individual patients with 4 different types of congenital heart disease were examined by Southern blot analysis using a cDNA probe which codes for the full length human ventricular myosin light chain 1. Restriction fragment length polymorphisms were detected in two families and were not associated with any type of congenital heart disease.
从9个家族以及13名患有4种不同类型先天性心脏病的无血缘关系个体患者中分离出基因组DNA,使用编码全长人心室肌球蛋白轻链1的cDNA探针通过Southern印迹分析进行检测。在两个家族中检测到限制性片段长度多态性,且其与任何类型的先天性心脏病均无关联。