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[里德-弗罗斯特模型的研究与改进]

[Study and improvement of Reed-Frost model].

作者信息

Mei J, Zeng G

机构信息

Jiangxi Provinial Hygiene and Epidemic Prevention Station, Nanchang.

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 1994 Apr;15(2):110-3.

PMID:7923332
Abstract

The purpose of this paper is to modify the Reed-Frost theory of epidemics with the underlying assumptions of the model including the occurrence of inapparent infections, and their influence on the course of the epidemic. With this model two epidemics were computed: (1) the Aycock outbreak of measles in a New England boy-boarding school in 1934; (2) the outbreak of chickenpox in a Shanghai kindergarten in 1950. The calculated and observed results were well in agreement. A substantial improvement in fitness was shown as measured by chi-square tests. As presented, the model offers a reasonably good explanation on the occurrence of inapparent infections and its effect on the pattern of the disease.

摘要

本文的目的是在包含隐性感染的发生及其对疫情进程影响的模型基本假设基础上,对里德 - 弗罗斯特流行病理论进行修正。利用该模型计算了两场疫情:(1)1934年新英格兰一所男校发生的艾科克麻疹疫情;(2)1950年上海一所幼儿园发生的水痘疫情。计算结果与观察结果吻合良好。通过卡方检验表明拟合度有显著提高。如前所述,该模型对隐性感染的发生及其对疾病模式的影响提供了较为合理的解释。

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