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丙泊酚用于儿科门诊患者的脉冲染料激光治疗

Propofol for pulsed dye laser treatments in paediatric outpatients.

作者信息

Vischoff D, Charest J

机构信息

Department of Anaesthesia, Sainte-Justine Hospital, Montreal, Canada.

出版信息

Can J Anaesth. 1994 Aug;41(8):728-32. doi: 10.1007/BF03015629.

Abstract

Pulsed dye laser is a new treatment for port-wine stains, congenital lesions in the cutaneous vascular plexus. We report our anesthetic experience with paediatric outpatients treated in the dermatology clinic. From April to November 1993, 48 ASA 1 children were anaesthetised for a total of 105 consecutive laser treatments. The youngest was eight months old, the oldest was 12 yrs old and most of the sessions (43%) were done for children aged from two to four years. Each received acetaminophen (10 mg.kg-1 p.o.) before treatment. A propofol infusion was chosen for anaesthesia to achieve early discharge and to reduce the incidence of postoperative emesis. The infusion was adjusted to maintain blood pressure within 20% of baseline and to keep the child immobile. The dose was progressively reduced during the procedure from 400 micrograms.kg-1.min-1 to 100 micrograms.kg-1.min-1. Fentanyl (2 micrograms.kg-1 i.v.) was added for analgesia. Respiration was spontaneous through a nasopharyngeal airway (air in oxygen 40%). Anaesthesia proceeded uneventfully in all cases and lasted for 15-30 min (63% of treatments), 30-45 min (28%) or 45-60 min (9%) according to the size of the lesion. The mean stay in the recovery room was 25.1 min and none of the patients experienced emesis. Our experience shows that general anaesthesia with propofol supplemented with fentanyl offers a rapid onset and awakening, a painless treatment and an immobile child. It is a safe solution to alleviate pain from repeated painful procedures even in small children under two years of age.

摘要

脉冲染料激光是治疗葡萄酒色斑(皮肤血管丛先天性病变)的一种新方法。我们报告了在皮肤科门诊治疗小儿门诊患者的麻醉经验。1993年4月至11月,48例美国麻醉医师协会(ASA)分级为1级的儿童接受了连续105次激光治疗的麻醉。最小的患儿8个月大,最大的12岁,大部分治疗(43%)针对2至4岁的儿童。每次治疗前均给予对乙酰氨基酚(口服10mg/kg)。选择丙泊酚输注进行麻醉,以实现早期出院并降低术后呕吐的发生率。调整输注速度以维持血压在基线的20%以内,并使患儿保持不动。在手术过程中,剂量从400μg·kg⁻¹·min⁻¹逐渐降至100μg·kg⁻¹·min⁻¹。添加芬太尼(静脉注射2μg/kg)用于镇痛。通过鼻咽气道(40%氧气中的空气)进行自主呼吸。所有病例麻醉过程均顺利,根据病变大小,麻醉持续15至30分钟(63%的治疗)、30至45分钟(28%)或45至60分钟(9%)。在恢复室的平均停留时间为25.1分钟,无一例患者出现呕吐。我们的经验表明,丙泊酚联合芬太尼全身麻醉起效快、苏醒快、治疗无痛且患儿不动。即使对于两岁以下的幼儿,它也是缓解重复疼痛操作疼痛的安全方法。

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