Rosalki S B
Department of Chemical Pathology and Human Metabolism, Royal Free Hospital and School of Medicine, London, UK.
Clin Chim Acta. 1994 May;226(2):143-50. doi: 10.1016/0009-8981(94)90211-9.
Bone-origin ALP in plasma may be readily quantified by WG-lectin methods and such measurements (reflecting osteoblastic activity) are useful in a wide variety of bone disorders. The studies summarized here have confirmed that ALP isoenzyme examination by these methods adds tissue specificity and diagnostic sensitivity to total ALP measurement.