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术后常规进行双功超声检查以筛查和监测深静脉血栓形成。对110例全髋关节置换术的调查。

Routine postoperative duplex ultrasonography screening and monitoring for the detection of deep vein thrombosis. A survey of 110 total hip arthroplasties.

作者信息

Grady-Benson J C, Oishi C S, Hanson P B, Colwell C W, Otis S M, Walker R H

机构信息

Division of Orthopaedic Surgery, Scripps Clinic and Research Foundation, La Jolla, CA 92037.

出版信息

Clin Orthop Relat Res. 1994 Oct(307):130-41.

PMID:7924025
Abstract

The use of duplex ultrasonography for routine noninvasive screening, monitoring, and management of deep venous thrombosis after total hip arthroplasty was evaluated. The reliability of duplex ultrasonography for detection of deep vein thrombosis was confirmed in an initial cohort of 51 total hip arthroplasty patients (102 lower extremities), demonstrating 91% sensitivity, 98% specificity, and 97% accuracy when compared with venography. A second cohort of 110 total hip arthroplasty patients using pneumatic compression stockings and aspirin as deep vein thrombosis prophylaxis underwent screening duplex ultrasonography of both lower extremities on postoperative Day 4. Duplex ultrasonography screening showed 10 (9.1%) patients with proximal deep vein thrombosis and 10 (9.1%) with distal deep vein thrombosis, all of whom were asymptomatic. The 10 patients with proximal deep vein thrombosis on duplex ultrasonography were prescribed therapeutic anticoagulation. Duplex ultrasonography subsequently confirmed resolution of proximal deep vein thrombosis in these patients before discontinuation of anticoagulation; none developed symptomatic pulmonary embolism through 12-month clinical followup. The 10 patients with distal deep vein thrombosis diagnosed by duplex ultrasonography were not treated with anticoagulation, but were monitored by serial duplex ultrasonography through postoperative Day 14 for propagation of distal to proximal deep vein thrombosis; none manifested symptomatic deep vein thrombosis or pulmonary embolism through 12-month clinical followup. The 90 patients with negative duplex ultrasonography results were followed clinically; 3 developed late symptomatic proximal deep vein thrombosis (1 of these later manifested pulmonary embolism). Therefore, duplex ultrasonography was used after total hip arthroplasty for the following: (1) to screen routinely in the hospital for asymptomatic proximal and distal deep vein thrombosis; (2) to monitor for potential propagation of distal to proximal deep vein thrombosis; (3) to minimize exposure to therapeutic anticoagulation by confirming the absence of proximal deep vein thrombosis in 97 of 110 patients; and (4) to demonstrate the effectiveness of mechanical and systemic deep vein thrombosis management by confirming the absence or resolution of deep vein thrombosis in all 110 patients.

摘要

对全髋关节置换术后深静脉血栓形成的常规无创筛查、监测及管理中双功超声检查的应用进行了评估。在最初的51例全髋关节置换术患者(102条下肢)队列中,证实了双功超声检查检测深静脉血栓形成的可靠性,与静脉造影相比,其敏感性为91%,特异性为98%,准确性为97%。第二组110例使用气动压迫袜和阿司匹林预防深静脉血栓形成的全髋关节置换术患者在术后第4天接受了双下肢的双功超声筛查。双功超声筛查显示10例(9.1%)患者存在近端深静脉血栓形成,10例(9.1%)存在远端深静脉血栓形成,所有这些患者均无症状。对双功超声检查显示近端深静脉血栓形成的10例患者给予了治疗性抗凝。双功超声随后证实这些患者在抗凝治疗停止前近端深静脉血栓形成已消退;在12个月的临床随访中,无一例发生有症状的肺栓塞。双功超声检查诊断为远端深静脉血栓形成的10例患者未接受抗凝治疗,但通过术后第14天的系列双功超声检查监测远端深静脉血栓形成向近端的扩展情况;在12个月的临床随访中,无一例出现有症状的深静脉血栓形成或肺栓塞。对双功超声检查结果为阴性的90例患者进行了临床随访;3例出现了晚期有症状的近端深静脉血栓形成(其中1例后来出现了肺栓塞)。因此,全髋关节置换术后使用双功超声检查用于以下方面:(1)在医院常规筛查无症状的近端和远端深静脉血栓形成;(2)监测远端深静脉血栓形成向近端的潜在扩展;(3)通过确认110例患者中有97例不存在近端深静脉血栓形成,尽量减少治疗性抗凝的暴露;(4)通过确认所有110例患者不存在深静脉血栓形成或深静脉血栓形成已消退,证明机械和全身深静脉血栓形成管理的有效性。

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