Kanzaki A, Yabuki S
Department of Neurology, Kochi Municipal Central Hospital.
Rinsho Shinkeigaku. 1994 May;34(5):511-3.
A 60-year-old woman was admitted to our hospital because of developing fever, visual loss, weakness in right upper limb, walking difficulty and difficulties of urination and defecation. There were memory disturbance, optic neuritis, ataxia and myelopathy. CSF cells and protein were increased. Cytomegalovirus (CMV) antibodies in the CSF were increased. T2-weighted images of brain MRI showed diffuse high signal intensity lesions in white matter. Gadolinium-enhanced MRI of cervical spinal cord showed diffuse spotty enhanced lesions. Corticosteroid treatment improved clinical symptoms and anti-CMV antibodies in the CSF. This is the first case report of ADEM associated with CMV infection.
一名60岁女性因出现发热、视力丧失、右上肢无力、行走困难及排尿和排便困难而入住我院。存在记忆障碍、视神经炎、共济失调和脊髓病。脑脊液细胞和蛋白增多。脑脊液中巨细胞病毒（CMV）抗体升高。脑部MRI的T2加权图像显示白质弥漫性高信号病变。颈椎脊髓钆增强MRI显示弥漫性斑点状强化病变。皮质类固醇治疗改善了临床症状及脑脊液中的抗CMV抗体。这是首例与CMV感染相关的急性播散性脑脊髓炎病例报告。
