He R, Bao K G
Department of Environment Health, Hubei Provincial Hygiene and Anti-epidemic Station, Wuhan.
Zhonghua Yu Fang Yi Xue Za Zhi. 1994 Mar;28(2):97-9.
Fifty-six male wistar rats were selected to study the effects of selenium and DTPA on cadmium excretion. Cadmium levels in urine, feces and tissues of the rats were determined with graphite stove method, and their kidneys were examined pathohistologically. Results showed selenium had stronger effects on cadmium excretion via feces in rats than DTPA did, and combination of both of them showed synergistic effects on it. Also, selenium could accelerate the recovery from kidney injury caused by cadmium, and combination of both of them showed synergism on it.
选取56只雄性Wistar大鼠研究硒和二乙三胺五乙酸（DTPA）对镉排泄的影响。采用石墨炉法测定大鼠尿液、粪便和组织中的镉含量，并对其肾脏进行病理组织学检查。结果表明，硒对大鼠粪便中镉排泄的影响比DTPA更强，二者联合使用对镉排泄具有协同作用。此外，硒可加速镉所致肾损伤的恢复，二者联合使用对此也具有协同作用。
