Liporace J D, Sperling M R, Dichter M A
Department of Neurology, University of Pennsylvania, Graduate Hospital, Philadelphia.
Epilepsia. 1994 Sep-Oct;35(5):1026-8. doi: 10.1111/j.1528-1157.1994.tb02549.x.
Carbamazepine (CBZ) therapy was associated with development of absence seizures in 4 adults with generalized epilepsy. Two patients had new appearance of absence seizures and 2 patients had recrudescence of remote absence seizures. The seizures abated after discontinuation of CBZ therapy or addition of ethosuximide (ESM) in 1 patient intolerant of valproate (VPA).
卡马西平(CBZ)治疗与4例全身性癫痫成人患者失神发作的发生有关。2例患者出现新发失神发作,2例患者既往有过的失神发作复发。在1例不耐受丙戊酸盐(VPA)的患者中,停用CBZ治疗或加用乙琥胺(ESM)后癫痫发作缓解。