McLaughlin J F, Bjornson K F, Astley S J, Hays R M, Hoffinger S A, Armantrout E A, Roberts T S
Department of Pediatrics, Children's Hospital and Medical Center, Seattle, WA 98105.
Dev Med Child Neurol. 1994 Sep;36(9):755-69. doi: 10.1111/j.1469-8749.1994.tb08187.x.
This is a prospective observational study of a consecutive series of 34 children with spastic cerebral palsy treated at a single center. 10 had spastic quadriplegia and 24 had spastic diplegia. All were followed for at least one year. After selective dorsal rhizotomy (SDR), all children received one month of physical therapy at the center and were prescribed a program of physical therapy in their community. The children were assessed before and one year after SDR and physical therapy, using the Ashworth Scale, deep tendon reflex response, range of motion and the Gross Motor Function Measure. The results show that there is often a decrease in lower-extremity spasticity and functional improvement after SDR with physical therapy, but that there is considerable variability in outcome. Randomized prospective clinical trials with masked objective outcome measures are needed to determine the efficacy of SDR.
这是一项对在单一中心接受治疗的34例痉挛型脑瘫患儿进行的前瞻性观察性研究。其中10例为痉挛性四肢瘫，24例为痉挛性双瘫。所有患儿均随访至少一年。在选择性背根切断术（SDR）后，所有患儿在该中心接受了一个月的物理治疗，并在其社区被安排了一个物理治疗方案。在SDR和物理治疗前及治疗一年后，使用Ashworth量表、深部腱反射反应、活动范围和粗大运动功能测量对患儿进行评估。结果表明，SDR联合物理治疗后，下肢痉挛通常会减轻，功能会改善，但结果存在相当大的变异性。需要采用客观结果指标进行盲法的随机前瞻性临床试验来确定SDR的疗效。
