Postulka A
Institut für Medizinische Mikrobiologie und Immunologie, Ruhr-Universität Bochum.
Immun Infekt. 1994 Aug;22(4):142-5.
230 clinical isolates of Acinetobacter species were characterized according to genospecies (new taxonomy), relative frequency of isolation, distribution in clinical samples and resistance pattern. A.baumannii was more frequently found than any other species (42%), followed by A.lwoffii (28%), although only 60% of the former "A.lwoffi" corresponds to the new A.lwoffii. The other 40%, formerly A.lwoffi, were shared by A.junii and A.haemolyticus. Concerning habitat and resistance pattern, remarkable differences between the new biotypes were found. A.baumannii and A.lwoffii were isolated mainly from swabs. A.calcoaceticus was most frequently cultivated from samples of the upper respiratory tract, and from blood cultures preferably A.baumannii and, more rarely, A.lwoffii and A.haemolyticus were isolated. A.baumannii showed multidrug resistance against beta-lactam antibiotics, most of the tested penicillins and cephalosporins. The two most susceptible species in our study were A.junii and A.lwoffii. Resistance to imipenem, aminoglycosides and quinolones was rare with all strains.
根据基因种(新分类法)、分离相对频率、在临床样本中的分布以及耐药模式,对230株不动杆菌属临床分离株进行了特征分析。鲍曼不动杆菌的分离频率高于其他任何菌种(42%),其次是洛菲不动杆菌(28%),不过之前的“洛菲不动杆菌”中只有60%对应新的洛菲不动杆菌。另外40%之前被归为洛菲不动杆菌,现归为琼氏不动杆菌和溶血不动杆菌。在栖息地和耐药模式方面,新生物型之间存在显著差异。鲍曼不动杆菌和洛菲不动杆菌主要从拭子中分离得到。醋酸钙不动杆菌最常从上呼吸道样本中培养出来,而从血培养中分离出的主要是鲍曼不动杆菌,较少见的是洛菲不动杆菌和溶血不动杆菌。鲍曼不动杆菌对β-内酰胺类抗生素、大多数受试青霉素和头孢菌素表现出多重耐药性。在我们的研究中,最敏感的两个菌种是琼氏不动杆菌和洛菲不动杆菌。所有菌株对亚胺培南、氨基糖苷类和喹诺酮类的耐药性都很罕见。