Soni G R
National Institute of Virology, Pune.
Indian J Med Res. 1994 Aug;100:57-8.
The effect of pregnancy on the protective immune response of mice to tissue culture-derived inactivated Japanese encephalitis (JE) Nakayama vaccine and to live sublethal doses of JE virus, was studied. Thirty per cent protection was found in mice, immunized with three doses of inactivated vaccine, before pregnancy and challenged after delivery. In contrast, all the mice immunized with two sublethal doses of JEV tolerated the challenge under similar condition.
研究了怀孕对小鼠针对组织培养来源的灭活日本脑炎（JE）中山株疫苗以及对亚致死剂量活JE病毒的保护性免疫反应的影响。在怀孕前用三剂灭活疫苗免疫并在分娩后进行攻击的小鼠中，发现有30%的保护率。相比之下，用两剂亚致死剂量的日本脑炎病毒（JEV）免疫的所有小鼠在类似条件下都耐受了攻击。
