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人类新生儿左右手握力反射强度与血清皮质醇水平及胎儿体位的关系。

Grasp-reflex strength from right and left hands in relation to serum cortisol level and fetal position in human neonates.

作者信息

Tan U, Zor N

机构信息

Department of Physiology, Medical Faculty, Ataturk University, Erzurum, Turkey.

出版信息

Int J Neurosci. 1994 Jan-Feb;74(1-4):27-32. doi: 10.3109/00207459408987226.

DOI:10.3109/00207459408987226
PMID:7928112
Abstract

The grasp-reflex strengths from right (R) and left (L) hands were studied in human neonates in relation to serum cortisol levels and fetal position. In males with right-ear out, there was no correlation between grasp-reflex strength from right hand and cortisol. The grasp-reflex strength from left hand significantly decreased as cortisol increased linearly in these subjects. In males with left-ear out, the grasp-reflex strengths from right and left hands were found to be negatively linearly correlated with serum cortisol level. In females with right-ear out, the grasp-reflex strength from right hand was not significantly correlated with cortisol, but grasp reflex from left hand linearly decreased as cortisol increased. In females with left-ear out, only the grasp reflex from right hand linearly increased with cortisol. Only in males with right-ear out, the R-L grasp-reflex strength linearly increased from left dominance toward right dominance. It was concluded that the stress hormone cortisol may be disadvantageous and/or advantageous for the prenatal development of the right and left brain according to fetal position; cortisol may also affect the emergence of cerebral lateralization.

摘要

研究了人类新生儿右手(R)和左手(L)的抓握反射强度与血清皮质醇水平及胎位的关系。在右耳朝外的男性中,右手抓握反射强度与皮质醇之间无相关性。在这些受试者中,随着皮质醇呈线性增加,左手抓握反射强度显著降低。在左耳朝外的男性中,发现右手和左手的抓握反射强度与血清皮质醇水平呈负线性相关。在右耳朝外的女性中,右手抓握反射强度与皮质醇无显著相关性,但随着皮质醇增加,左手抓握反射呈线性降低。在左耳朝外的女性中,只有右手抓握反射随皮质醇呈线性增加。只有在右耳朝外的男性中,R-L抓握反射强度从左优势向右侧优势呈线性增加。得出的结论是,应激激素皮质醇根据胎位可能对左右脑的产前发育不利和/或有利;皮质醇也可能影响大脑侧化的出现。

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