Kangas E, Matikainen M, Mattila J
Department of Surgery, University Hospital, Tampere, Finland.
Int Surg. 1994 Apr-Jun;79(2):120-3.
The diagnosis of "indeterminate colitis" was found in 6 patients of 147 operated patients (4%) as compared to the indeterminate diagnosis in 59 of 465 non-operated colitis patients (13%) at the register of inflammatory bowel diseases of Tampere University Hospital. The long-term natural course of the six surgically treated "indeterminate colitis" patients was analysed. The term "indeterminate colitis" included macroscopically either Crohn's colitis or ulcerative colitis which histologically remained indeterminate both pre and peroperatively. Clinicopathological follow-up after the median 5 1/2 years indicated typical Crohn's disease in one case and probable in two cases. However, the final diagnosis remained indeterminate in three cases. The results of the present study showed that patients with indeterminate colitis may have a tendency for Crohn's colitis in the long-term follow-up and thus should be considered when planning an ileal pouch-anal anastomosis.
在坦佩雷大学医院炎症性肠病登记处，147例接受手术治疗的患者中有6例（4%）被诊断为“不确定性结肠炎”，而465例未接受手术治疗的结肠炎患者中有59例（13%）诊断不明确。分析了6例接受手术治疗的“不确定性结肠炎”患者的长期自然病程。“不确定性结肠炎”这一术语在宏观上包括克罗恩结肠炎或溃疡性结肠炎，其在术前和术中组织学上仍不明确。中位随访5.5年后的临床病理随访表明，1例为典型的克罗恩病，2例可能为克罗恩病。然而，3例的最终诊断仍不明确。本研究结果表明，不确定性结肠炎患者在长期随访中可能有患克罗恩结肠炎的倾向，因此在计划回肠储袋肛管吻合术时应予以考虑。
