Persson L
Division of Nuclear Safety, IAEA, Vienna, Austria.
Health Phys. 1994 Nov;67(5):471-6. doi: 10.1097/00004032-199411000-00002.
The Auger electron effect is of importance in radiation protection related to work in radiobiology, radiophysics, and nuclear medicine. Radionuclides that emit Auger electrons are widely used in nuclear medicine (99mTc, 123I, and 201Tl) and in biomedical research (51Cr and 125I). They are also present in the environment (40K). Therefore, calculation of the absorbed dose and equivalent dose to tissues from these incorporated radionuclides is important for risk assessment. Depending on the subcellular distribution of the radionuclide, the biological effects caused by cell-incorporated Auger emitters can be as severe as those from high-linear energy transfer (LET) alpha particles. However, the recently adopted recommendations of the International Commission on Radiological Protection in Publication No. 60 do not provide guidance on calculating the equivalent dose for these radionuclides. A better understanding of the effects of Auger electrons is required to estimate the equivalent doses, and further research in this field is appropriate. There are good reasons to consider the Auger electron effect not only in medical radiation protection of patients but also in the context of annual limits of intake for workers and the public.
俄歇电子效应在与放射生物学、放射物理学及核医学工作相关的辐射防护中具有重要意义。发射俄歇电子的放射性核素广泛应用于核医学（锝-99m、碘-123和铊-201）及生物医学研究（铬-51和碘-125）。它们也存在于环境中（钾-40）。因此，计算这些摄入体内的放射性核素对组织的吸收剂量和当量剂量对于风险评估很重要。根据放射性核素的亚细胞分布情况，细胞内掺入的俄歇发射体所引起的生物效应可能与高传能线密度（LET）的α粒子所引起的效应一样严重。然而，国际放射防护委员会第60号出版物中最近采用的建议并未提供关于计算这些放射性核素当量剂量的指导。为了估算当量剂量，需要更好地了解俄歇电子的效应，并且在该领域进行进一步研究是恰当的。有充分的理由不仅在患者的医学辐射防护中考虑俄歇电子效应，而且在工作人员和公众的年摄入量限值背景下也予以考虑。
