Lerch M M, Adler G
Department of Medicine I, Ulm University Medical School, Germany.
Int J Pancreatol. 1994 Jun;15(3):159-70.
Experimental animal models have been employed to study pancreatitis for more than a century. Although not always related to the disease in humans, they have contributed greatly to our current understanding of the pathophysiology and cell biology of this disease. They have also become a standard tool for testing new and promising treatments against pancreatitis. The following article will review the most commonly used experimental models of pancreatitis and some of the lessons we have learned from them.
一个多世纪以来,实验动物模型一直被用于研究胰腺炎。尽管它们并不总是与人类疾病相关,但它们为我们目前对这种疾病的病理生理学和细胞生物学的理解做出了巨大贡献。它们也已成为测试针对胰腺炎的新的、有前景的治疗方法的标准工具。以下文章将回顾最常用的胰腺炎实验模型以及我们从它们身上学到的一些经验教训。