Sesti F, De Santis L, Farné C, Mantenuto L, Piccione E
Department of Obstetrics and Gynecology, Tor Vergata University of Rome, Italy.
J Reprod Med. 1994 Jun;39(6):441-4.
This paper reports the clinical and virologic results of CO2 laser treatment for squamous intraepithelial lesions in 154 patients. On the basis of cervical canal involvement, vaporization or conization was performed. Failure rates following the first and second treatments were 4.5% and 0%, respectively. However, human papillomavirus persistence in several women with completely normal follow-up suggests that one of the possible mechanisms of failure could be reexposure of the healing area to a viral reservoir within the "normal" epithelium.
本文报告了154例鳞状上皮内病变患者接受二氧化碳激光治疗的临床和病毒学结果。根据宫颈管受累情况，进行汽化或锥切术。首次治疗和第二次治疗后的失败率分别为4.5%和0%。然而，在随访完全正常的几名女性中，人乳头瘤病毒持续存在，这表明失败的一种可能机制可能是愈合区域再次暴露于“正常”上皮内的病毒储存库。
