Brown D L, Roberts D J, Miller W A
Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115.
J Ultrasound Med. 1994 Aug;13(8):613-6. doi: 10.7863/jum.1994.13.8.613.
Echogenic foci within the left ventricle of the heart have been found in a minority of fetuses and generally are believed to be a normal variant. The cause and exact location of these foci have remained speculative, however. We identified three fetuses with this sonographic finding in whom pathologic correlation was available. The only consistent histologic finding present in all three fetuses was mineralization within a papillary muscle; the chordae tendineae were normal. One of the three fetuses had trisomy 21. Echogenic foci within the left ventricle of the fetal heart represent papillary muscle mineralization. Until more data are available to investigate any possible association with aneuploidy, an echogenic focus in the left ventricle should still be considered a normal variant.
少数胎儿的心脏左心室内发现有回声灶，一般认为这是一种正常变异。然而，这些病灶的成因及确切位置仍存在推测性。我们确定了三名有此超声检查结果且有病理对照的胎儿。所有三名胎儿唯一一致的组织学发现是乳头肌内有矿化；腱索正常。三名胎儿中有一名患有21三体综合征。胎儿心脏左心室内的回声灶代表乳头肌矿化。在有更多数据可用于研究与非整倍体的任何可能关联之前，左心室内的回声灶仍应被视为正常变异。
