Cigánek L, Sramka M, Nádvorník P, Fritz G
Acta Neurochir (Wien). 1976(23 Suppl):201-4. doi: 10.1007/978-3-7091-8444-8_31.
In 81 patients with intractable epileptic seizures 121 stereo-electroencephalographic (SEEG) examinations and 91 operations with stereoencephalotomy (SET) were carried out. SEEG and SET targets were chosen in 22 different subcortical structures and in the medial frontal cortex. In 6 of 18 temporal epilepsy cases SET was followed by classical hippocampectomy. With the exception of temporal lobe cases all others were unsuitable for classical neurosurgery. Of 61 controlled patients 24.5% were cured or greatly improved cured, 39.5% improved and 36% unimproved; Correlations among the clinical, EEG and SEEG findings; SET and therapeutic effects are discussed together with the role of stereotactic procedures. In our experience (Cigánek 1962) among patients unsuccessfully treated by conservative methods over 60% are unsuitable for classical procedures based on the criteria of the Montreal neurosurgical school, because of the absence of leading epileptogenic area or because they represent cases with completely or almost completely generalized seizures. In these cases stereotaxy offers prospects diagnostic refinement and treatment.
对81例顽固性癫痫发作患者进行了121次立体定向脑电图(SEEG)检查,并实施了91次立体定向脑切开术(SET)。SEEG和SET的靶点选择在22个不同的皮质下结构及额叶内侧皮质。18例颞叶癫痫患者中有6例在SET后进行了经典的海马切除术。除颞叶病例外,其他所有病例均不适合经典神经外科手术。在61例病情得到控制的患者中,24.5%治愈或显著改善,39.5%有所改善,36%未改善;讨论了临床、脑电图和SEEG检查结果之间的相关性、SET与治疗效果,以及立体定向手术的作用。根据我们的经验(Cigánek,1962年),在采用保守方法治疗失败的患者中,超过60%因无明确的致痫灶或属于完全或几乎完全全身性发作病例,不符合蒙特利尔神经外科学派的标准,不适合经典手术。在这些病例中,立体定向手术为诊断细化和治疗提供了前景。