Kim D E, Berlowitz D R
Geriatric Service, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA 01730.
JAMA. 1994 Nov 9;272(18):1447-52.
To determine the usefulness of a routine, comprehensive battery of laboratory tests in a severely impaired elderly nursing home population.
Prospective observational survey.
Skilled nursing facility wards of a geriatric and extended care veterans hospital.
Consecutive sample of 108 veterans with severe cognitive and functional impairments, who had been hospitalized at least 6 months.
Proportions of tests categorized as screening, monitoring, follow-up, or diagnostic; frequency of abnormal test results, interventions warranted and performed on the basis of these abnormalities, and beneficial or adverse effects.
Of 6771 individual nondiagnostic tests performed, 17.2% yielded abnormal results; of these, 33.3% were new. However, only 0.2% of tests resulted in patient benefit. Of 989 panels performed, 31.0% contained at least one abnormality, but only 1.0% of panels (10 patients) yielded any benefit. Overall usefulness was related to the purpose of the testing, with 31.5% of screening tests yielding abnormalities, compared with 45.5%, 78.2%, and 68.7% of monitoring, follow-up, and diagnostic panels, respectively (P < .05 for each compared with screening panels). None of the screening panels detected an abnormality that led to patient benefit, compared with 1.0%, 1.4%, and 3.0% of monitoring, follow-up, and diagnostic panels.
Routine comprehensive laboratory panels may not be warranted in the most severely impaired elderly patients in long-term care settings. Discontinuing true screening tests and limiting testing strictly to monitoring, follow-up, or diagnostic purposes could minimize the costs of laboratory assessment without losing its potential benefits.
确定一套常规、全面的实验室检查在严重失能老年疗养院人群中的作用。
前瞻性观察性调查。
一家老年和长期护理退伍军人医院的专业护理设施病房。
连续抽取108名患有严重认知和功能障碍、已住院至少6个月的退伍军人作为样本。
分类为筛查、监测、随访或诊断的检查比例;异常检查结果的频率、基于这些异常情况而进行的必要干预及实施情况,以及有益或有害影响。
在进行的6771项非诊断性单项检查中,17.2%的检查结果异常;其中,33.3%为新发现的异常。然而,只有0.2%的检查对患者有益。在进行的989组检查中,31.0%的组至少有一项异常,但只有1.0%的组(10名患者)有任何获益。总体作用与检查目的相关,筛查检查中有31.5%出现异常,而监测、随访和诊断组的这一比例分别为45.5%、78.2%和68.7%(与筛查组相比,每组P<0.05)。与监测、随访和诊断组分别为1.0%、1.4%和3.0%相比,筛查组未检测到任何能使患者获益的异常情况。
在长期护理环境中,对于最严重失能的老年患者,可能无需进行常规的全面实验室检查。停止真正的筛查检查,并将检查严格限制于监测、随访或诊断目的,可在不损失潜在益处的情况下将实验室评估成本降至最低。