Akiyama H, Ohta S, Shoji K, Suzuki M
Department of Anesthesiology, Akita University School of Medicine.
Masui. 1994 Jul;43(7):1069-72.
A 75-year-old female with a history of cerebral infarction fell into sudden hypotension (mean blood pressure of around 46 mmHg) and severe anemia (hematocrit < or = 10%; minimum hemoglobin concentration of 2.0 g.dl-1) of approximately one hour due to massive hemorrhage during surgical removal of pheochromocytoma originated in the right adrenal gland. Nevertheless, she recovered from the unconsciousness after over 9 hours postoperatively. It is suggested that major reasons for her escaping from the brain damage, in spite of the low cerebral perfusion pressure, might be the decreased cerebral oxygen consumption due to the intraoperative mild hypothermia (31.5 degrees C) and the avoidance due to hemodilution of the extremely low cerebral blood flow.
一名75岁有脑梗死病史的女性,在手术切除起源于右肾上腺的嗜铬细胞瘤过程中因大量出血,陷入约一小时的突然低血压(平均血压约46mmHg)和严重贫血(血细胞比容≤10%;最低血红蛋白浓度为2.0g.dl-1)。然而,术后9个多小时后她从昏迷中苏醒。尽管脑灌注压较低,但她未发生脑损伤的主要原因可能是术中轻度低温(31.5摄氏度)导致脑氧消耗减少,以及血液稀释避免了极低的脑血流量。