Nishimura T, Sugita K, Aoki S, Takagi M
Department of Pediatrics, Osaka Medical College.
Jpn J Antibiot. 1994 Jul;47(7):940-9.
We have carried out bacteriological and clinical studies on L-627. The results are summarized as follows. Treatment with L-627 was made in 14 cases of pediatric bacterial infections including 5 cases of pneumonia and 2 cases each of tonsillitis, urinary tract infection and one case each of colitis, and phlegmon. Results obtained were excellent in 11 cases, good in 2 cases and poor in one case. The bacteriological effect of L-627 was excellent, all causative organisms (Staphylococcus aureus one strain, Streptococcus pyogenes 2 strains, Streptococcus pneumoniae 3 strains, Escherichia coli 3 strains, Haemophilus influenzae one strain, Haemophilus parainfluenzae one strain) were eradicated. No significant side effects due to the drug were observed in any cases, except 2 cases each of elevated eosinophil counts and elevated platelet counts.
我们对L-627进行了细菌学和临床研究。结果总结如下。对14例小儿细菌感染患者使用了L-627进行治疗，其中包括5例肺炎、2例扁桃体炎、2例尿路感染、1例结肠炎和1例蜂窝织炎。11例效果极佳，2例良好，1例较差。L-627的细菌学效果极佳，所有致病菌（金黄色葡萄球菌1株、化脓性链球菌2株、肺炎链球菌3株、大肠杆菌3株、流感嗜血杆菌1株、副流感嗜血杆菌1株）均被根除。除2例嗜酸性粒细胞计数升高和2例血小板计数升高外，未观察到该药物引起的明显副作用。
