Weeks J R
Adv Prostaglandin Thromboxane Res. 1976;1:395-401.
The prostaglandins have diverse cardiovascular effects, differing not only among themselves but also according to the organ affected and the species. Some of the pharmacological actions of the prostaglandins may have practical application in hypertensive crises, shock, peripheral vascular disease, and to maintain the patency of the ductus arteriosus in congenital heart malformations. They may play physiological roles as locally produced modulators or regulators of kidney function and blood flow to specific organs or tissues. Such roles are yet to be firmly established.
前列腺素具有多种心血管效应，不仅不同种类的前列腺素之间存在差异，而且根据所影响的器官和物种的不同也有所不同。前列腺素的某些药理作用可能在高血压危象、休克、外周血管疾病以及维持先天性心脏畸形中动脉导管的通畅方面有实际应用。它们可能作为局部产生的肾功能调节剂或特定器官或组织血流的调节剂发挥生理作用。但这些作用尚未得到确凿证实。
