Kim J Y, Chang B L
Department of Ophthalmology, Korea Veterans Hospital, Seoul.
Korean J Ophthalmol. 1994 Jun;8(1):14-9. doi: 10.3341/kjo.1994.8.1.14.
To evaluate the histopathologic changes after an inferior oblique marginal myotomy with local injection of triamcinolone, an inferior oblique marginal myotomy was performed in 14 white rabbits and they were divided into 2 groups, one group with a local injection of triamcinolone and the other group without triamcinolone injection after a myotomy. At the postoperative one month, an edema of the muscle fibers and an infiltration of the inflammatory cells were observed and at postoperative three months, a fibrous tissue ingrowth around the muscle fibers and an atrophy of the muscle fibers were found and those changes were less prominant in the group with triamcinolone injection. The local injection of triamcinolone after the inferior oblique marginal myotomy would help in decreasing the fibrous tissue ingrowth and the formation of the scar tissue, thus it could be used in augmenting the effect of the inferior oblique marginal myotomy.
为评估下斜肌边缘肌切开术联合局部注射曲安奈德后的组织病理学变化,对14只白兔进行下斜肌边缘肌切开术,并将它们分为两组,一组在肌切开术后局部注射曲安奈德,另一组不注射曲安奈德。术后1个月观察到肌纤维水肿和炎性细胞浸润,术后3个月发现肌纤维周围有纤维组织长入和肌纤维萎缩,且这些变化在注射曲安奈德的组中不太明显。下斜肌边缘肌切开术后局部注射曲安奈德有助于减少纤维组织长入和瘢痕组织形成,因此可用于增强下斜肌边缘肌切开术的效果。