Yamagami S, Araie M, Mori M, Mishima K
Eye Clinic, JR Tokyo General Hospital, Japan.
Jpn J Ophthalmol. 1994;38(1):71-9.
Cataract extraction and posterior chamber intraocular lens (PC-IOL) implantation was carried out in 45 glaucoma eyes that had undergone glaucoma filtering surgery (Group A), and in 47 glaucoma eyes in which intraocular pressure (IOP) was well controlled with medication (Group B). To analyze the effects of PC-IOL implantation on the control of IOP and the functioning of the filtering bleb, a life-table analysis using the Kaplan-Meier method was carried out. In Group A the probability that IOP control will not worsen at 2 years was 56 +/- 12 (SE)% in eyes where a functioning filtering bleb had existed preoperatively. The probability that the filtering bleb was not cicatrized at 2 years postoperatively was 44 +/- 11 (SE)%. In Group B the postoperative IOP on the first postoperative day was significantly higher than the preoperative level in primary open angle glaucoma (POAG) eyes, while no such difference was seen in primary angle closure glaucoma (PACG) eyes. The postoperative IOP was significantly lower than the preoperative level from 3 to 6 months postoperatively in POAG eyes and from 1 to 12 months postoperatively in PACG eyes. Medication did not differ significantly pre- and postoperatively. In 64 +/- 11 (SE)% of POAG and 63 +/- 15% of PACG eyes the IOP control did not worsen at 2 years. In 70% of the eyes the IOP control improved postoperatively, and was maintained for 2 years with the probability of 44 +/- 12 (SE)%.
对45只已接受青光眼滤过手术的青光眼患眼（A组）以及47只眼压通过药物得到良好控制的青光眼患眼（B组）进行了白内障摘除及后房型人工晶状体（PC-IOL）植入术。为分析PC-IOL植入对眼压控制及滤过泡功能的影响，采用Kaplan-Meier方法进行了寿命表分析。在A组中，术前存在功能良好滤过泡的患眼中，眼压控制在2年内不恶化的概率为56±12（SE）%。术后2年滤过泡未瘢痕化的概率为44±11（SE）%。在B组中，原发性开角型青光眼（POAG）患眼术后第1天的眼压显著高于术前水平，而原发性闭角型青光眼（PACG）患眼中未观察到这种差异。POAG患眼术后3至6个月以及PACG患眼术后1至12个月的眼压显著低于术前水平。术前和术后用药情况无显著差异。在POAG患眼的64±11（SE）%以及PACG患眼的63±15%中，眼压控制在2年内未恶化。在70%的患眼中，眼压控制术后得到改善，并以44±12（SE）%的概率维持2年。
