Kurokawa K, Suzuki T, Suzuki K, Yamanaka H
Department of Urology, Gunma University School of Medicine.
Nihon Hinyokika Gakkai Zasshi. 1994 Aug;85(8):1243-7. doi: 10.5980/jpnjurol1989.85.1243.
We examined the distribution of interstitial temperatures during balloon lasertherapy, using 4 mongrel canines. The laser equipment (CL50FS, SLT Japan Co. Ltd. Tokyo, Japan) consisted of Nd:YAG laser that produced 360 spindle-shaped radiation from a laser balloon (2 cm long) with a water-cooled circulation system. By measuring the temperature 3-5 minutes after the beginning of the treatment, we obtained following results. The temperature of the bladder neck and urethral sphincter remained below 42 degrees C except under extreme conditions. The temperature at a 6 mm depth from the prostatic urethra rose as laser energy increased, but was not affected by increased circulation of cooling water. The temperature at a 10 mm depth from the prostatic urethra was not affected by either increased laser energy or increased circulation of cooling water. We concluded that the limit of tissue cooling is within 6 mm and direct transmission of laser energy is within 10 mm. Distribution of the tissue temperature peaked at a 6 mm depth in the prostatic urethra. When cooling water was circulated at a 200 ml/min and laser-energy was generated at 30 W, the temperature distribution demonstrated that at a 4-10 mm depth from the prostatic urethra reached over 45 degrees C and at a 6 mm depth from the prostatic urethra, a peak of 52 degrees C was obtained. The possibility of thermotherapy of the prostate was suggested.
我们使用4只杂种犬研究了球囊激光治疗期间间质温度的分布情况。激光设备（CL50FS，日本东京SLT株式会社）由Nd:YAG激光组成，该激光通过带有水冷循环系统的激光球囊（2厘米长）产生360个纺锤形辐射。通过在治疗开始后3 - 5分钟测量温度，我们得到了以下结果。除了在极端情况下，膀胱颈和尿道括约肌的温度保持在42摄氏度以下。距前列腺尿道6毫米深处的温度随着激光能量的增加而升高，但不受冷却水循环增加的影响。距前列腺尿道10毫米深处的温度既不受激光能量增加的影响，也不受冷却水循环增加的影响。我们得出结论，组织冷却的极限在6毫米以内，激光能量的直接传输在10毫米以内。组织温度分布在前列腺尿道6毫米深处达到峰值。当冷却水以200毫升/分钟的速度循环且激光能量以30瓦产生时，温度分布表明距前列腺尿道4 - 10毫米深处的温度超过45摄氏度，在距前列腺尿道6毫米深处获得了52摄氏度的峰值。这提示了前列腺热疗的可能性。
