蚕食性角膜溃疡中的自身免疫现象。

Autoimmune phenomenon in Mooren's ulcer.

作者信息

Brown S I, Mondino B J, Rabin B S

出版信息

Am J Ophthalmol. 1976 Dec;82(6):835-40. doi: 10.1016/0002-9394(76)90058-1.

Abstract

Direct immunofluorescent techniques demonstrated immunoglobulins localized to the conjunctival epithelium in three cases of Mooren's ulcer. In addition, complement was found in association with the immunoglobulins in the two active cases. Circulating antibodies to the conjunctival and corneal epithelium were demonstrated by indirect immunofluorescent techniques in all three patients. Further immunological examinations of the three cases failed to demonstrate other significant immune alterations.

摘要

直接免疫荧光技术显示，在3例蚕食性角膜溃疡患者中，免疫球蛋白定位于结膜上皮。此外，在2例活动期病例中发现补体与免疫球蛋白相关。间接免疫荧光技术证实，所有3例患者均存在针对结膜和角膜上皮的循环抗体。对这3例病例的进一步免疫学检查未发现其他明显的免疫改变。