Brown S I
Trans Ophthalmol Soc U K (1962). 1978 Sep;98(3):390-2.
It is probable that the traditional definition of Mooren's ulcer involving relentless progression should be modified. Many eyes have been seen with corneal ulcers which have the clinical diagnosis of Mooren's ulcer but respond to varying medications and to conjunctival excision. The ulcers can progress, however, in spite of all therapy, and in these cases, we recommend removal of the remaining corneal stroma, followed by penetrating corneal transplantation. Patients with Mooren's ulcer exhibit both cell-mediated and humoral immunological phenomena but, in a small series, did not respond to immunotherapy.
可能需要修改蚕食性角膜溃疡传统定义中关于病情持续进展这一描述。我们已观察到许多角膜溃疡患者，临床诊断为蚕食性角膜溃疡，但对各种药物及结膜切除术均有反应。然而，尽管进行了所有治疗，溃疡仍可能进展，对于这些病例，我们建议切除剩余角膜基质，随后进行穿透性角膜移植。蚕食性角膜溃疡患者表现出细胞介导和体液免疫现象，但在一小系列病例中，对免疫治疗无反应。
