Rubonis A V, Colby S M, Monti P M, Rohsenow D J, Gulliver S B, Sirota A D
Providence Veterans Affairs Medical Center, Brown University, Providence, Rhode Island 02912.
J Stud Alcohol. 1994 Jul;55(4):487-94. doi: 10.15288/jsa.1994.55.487.
The purpose of this study was twofold: to investigate gender differences in alcohol cue reactivity, and to study the effect of individualized mood induction on cue reactivity. Male (n = 38) and female (n = 19) alcoholics were exposed to an alcoholic beverage before and after mood induction to assess their reactivity to the beverage cues. The mood induction was based on a situation the subject had identified as being high risk for relapse. Subjects showed urge and salivary reactivity in response to alcohol beverage cues prior to mood induction, and the induction of mood enhanced urge reactivity in both men and women. Analyses with alcohol urge reactors (subjects that demonstrate an increased urge to drink alcohol in response to an alcoholic beverage cue) suggested that women show more urge reactivity in response to negative moods than do men. No gender differences were seen in reactivity to beverage cues alone. These results identify an important gender difference in the effect of negative moods on cue reactivity and suggest that negative mood situations may place women at a higher risk for relapse than men.
一是调查酒精线索反应性中的性别差异，二是研究个性化情绪诱导对线索反应性的影响。男性（n = 38）和女性（n = 19）酗酒者在情绪诱导前后接触酒精饮料，以评估他们对饮料线索的反应性。情绪诱导基于受试者确定为复发高风险的一种情况。在情绪诱导之前，受试者对酒精饮料线索表现出冲动和唾液反应性，情绪诱导增强了男性和女性的冲动反应性。对酒精冲动反应者（即对酒精饮料线索表现出饮酒冲动增加的受试者）的分析表明，女性在面对负面情绪时比男性表现出更多的冲动反应性。在仅对饮料线索的反应性方面未发现性别差异。这些结果确定了负面情绪对线索反应性影响方面的一个重要性别差异，并表明负面情绪情况可能使女性比男性面临更高的复发风险。
