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枸橼酸镓Ga 67扫描:对淋巴瘤患者的临床应用价值

Gallium citrate Ga 67 scanning: clinical usefulness in lymphoma patients.

作者信息

Seabold J E, Votaw M L, Keyes J W, Foley W D, Balachandran S, Gill S P

出版信息

Arch Intern Med. 1976 Dec;136(12):1370-4.

PMID:793551
Abstract

Gallium citrate Ga 67 (67Ga) scans were performed in 50 consecutive lymphoma patients who underwent routine staging. The overall accuracy of 67Ga scans was greater than 80% for all nodal sites except the spleen (68%). Sensitivity was greater than 88% in the neck and mediastinum, 67% in the abdomen-pelvis, and 33% for the spleen. Specificity was greater than 85% for all nodal sites except for the mediastinum (67%). The accuracy of pedal lymphangiograms was 75%, sensitivity 87%, and specificity 68%. Gallium 67 scans complemented the lymphogram in the abdomen-pelvis but, due to limited sensitivity and high number of equivocal studies (16%), did not replace it. Infraclavicular, pectoral, and mediastinal lesions were detected by 67Ga scans when missed by other means. In 20% to 25% of patients, 67Ga scans provided information not afforded by other diagnostic studies and are therefore considered an important staging procedure for lymphoma patients.

摘要

对50例接受常规分期的淋巴瘤患者进行了枸橼酸镓Ga 67(67Ga)扫描。除脾脏(68%)外,67Ga扫描对所有淋巴结部位的总体准确率均高于80%。颈部和纵隔的敏感性高于88%,腹盆腔为67%,脾脏为33%。除纵隔(67%)外,所有淋巴结部位的特异性均高于85%。足部淋巴管造影的准确率为75%,敏感性为87%,特异性为68%。67Ga扫描在腹盆腔补充了淋巴管造影,但由于敏感性有限且有大量可疑研究(16%),无法取代淋巴管造影。当其他方法漏诊时,67Ga扫描可检测到锁骨下、胸肌和纵隔病变。在20%至25%的患者中,67Ga扫描提供了其他诊断研究无法提供的信息,因此被认为是淋巴瘤患者重要的分期检查方法。

相似文献

1
Gallium citrate Ga 67 scanning: clinical usefulness in lymphoma patients.枸橼酸镓Ga 67扫描:对淋巴瘤患者的临床应用价值
Arch Intern Med. 1976 Dec;136(12):1370-4.
2
Gallium-67-citrate scanning for the localization and staging of lymphomas.用于淋巴瘤定位和分期的枸橼酸镓-67扫描。
J Nucl Med. 1975 Apr;16(4):255-60.
3
Scintigraphic evaluation of lymphoma: a comparative study of 67Ga-citrate and 111In-Bleomycin.淋巴瘤的闪烁显像评估:枸橼酸镓67与博来霉素铟111的对比研究
Radiology. 1977 Jun;123(3):687-94. doi: 10.1148/123.3.687.
4
The value of gallium-67 scanning in upper abdominal lymphomas.镓-67扫描在上腹部淋巴瘤中的价值。
Med J Aust. 1976 Jul 31;2(5):170-2. doi: 10.5694/j.1326-5377.1976.tb134451.x.
5
Role of 67gallium citrate scanning in the management of non-Hodgkin's lymphoma.枸橼酸镓扫描在非霍奇金淋巴瘤治疗中的作用。
Cancer. 1975 Nov;36(5):1690-741. doi: 10.1002/1097-0142(197511)36:5<1690::aid-cncr2820360524>3.0.co;2-y.
6
The value of bowel preparation in Ga-67 citrate scanning: concise communication.
J Nucl Med. 1977 Sep;18(9):886-9.
7
Se75 selenomethionine isotope lymphography in lymphoma: correlation with lymphangiography.
Am J Roentgenol Radium Ther Nucl Med. 1970 Aug;109(4):793-802. doi: 10.2214/ajr.109.4.793.
8
[Radioisotope scanning of neoplasms. 4. 67Ga scintigram of the chest].[肿瘤的放射性同位素扫描。4. 胸部镓-67闪烁扫描图]
Rinsho Hoshasen. 1975 Sep;20(9):781-3.
9
[Abdominal lymph node scintigraphy in lymphoreticular systemic diseases].
Med Klin. 1971 May 21;66(21):781-4.
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Scanning malignant neoplasms with gallium 67.用镓67扫描恶性肿瘤。
JAMA. 1970 May 18;212(7):1182-91.

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Sultan Qaboos Univ Med J. 2015 Aug;15(3):e338-43. doi: 10.18295/squmj.2015.15.03.006. Epub 2015 Aug 24.