Castelli L, Zlotnik H, Ponti R, Vidotto V
Laboratorio Analisi Chimico-Cliniche e Microbiologiche, Ospedale Amedeo di Savoia, Torino, Italy.
Mycopathologia. 1994 Jun;126(3):131-6. doi: 10.1007/BF01103766.
Nocardiosis is a well-described infection in immunocompromised patients, and has been rarely documented in patients with AIDS. Nocardia asteroides is the most frequently isolated etiologic agent. Rare cases are due to N. brasiliensis and N. otitidiscaviarum. This work describes the first case of nocardiosis in Italy caused by N. otitidiscaviarum in an AIDS patient. A 31 year-old intravenous drug abuser with a diagnosis of full-blown AIDS, presented with high fever and lymphadenitis with a fistula draining copious purulent discharge. Broad-spectrum antibiotic therapy was initiated, but the patient did not shown any improvement. Direct examination of the pus revealed numerous gram positive rods. When cultured N. otitidiscavarium was isolated and identified by morphological and biochemical tests.
诺卡菌病在免疫功能低下患者中是一种广为人知的感染，而在艾滋病患者中鲜有记录。星形诺卡菌是最常分离出的病原体。罕见病例由巴西诺卡菌和耳炎诺卡菌引起。本文报道了意大利首例由耳炎诺卡菌引起的艾滋病患者诺卡菌病。一名31岁的静脉吸毒者，被诊断为全面性艾滋病，出现高热和淋巴结炎，伴有一个排出大量脓性分泌物的瘘管。开始使用广谱抗生素治疗，但患者未见任何改善。对脓液的直接检查发现了大量革兰氏阳性杆菌。培养后，通过形态学和生化试验分离并鉴定出耳炎诺卡菌。
