Brouwer K J, Boxma H, Dokter J
Zuiderziekenhuis, afd. Heelkunde, Rotterdam.
Ned Tijdschr Geneeskd. 1994 Sep 3;138(36):1819-22.
Toxic epidermal necrolysis (TEN; Lyell's disease) was diagnosed in three patients: an 8-year-old boy and two women aged 39 and 25. Treatment consisted of daily sterile wound care using a synthetic wound covering, oral as well as tube feeding and administration of fluid, electrolytes and albumin. Sepsis developed in 2 patients, and was treated with specific antibiotics. Irreversible sight loss developed in 1 patient. A burns centre offers optimal conditions for treatment because of the combined availability of both nursing and medical expertise and of the required infrastructure needed for antisepsis, climate control and intensive care.
三名患者被诊断为中毒性表皮坏死松解症（TEN；莱尔氏病）：一名8岁男孩以及两名分别为39岁和25岁的女性。治疗包括每日使用合成伤口覆盖物进行无菌伤口护理、口服及管饲喂养以及补充液体、电解质和白蛋白。两名患者发生了败血症，并接受了特效抗生素治疗。一名患者出现了不可逆的视力丧失。烧伤中心提供了最佳的治疗条件，因为它兼具护理和医疗专业知识，以及防腐、气候控制和重症监护所需的基础设施。
