Anguissola G B, Mangiarotti R, Pierini A, Lubatti L, Conti E, Arpesani A, Burdick L, Trazzi R
Cattedra di Anestesiologia e Rianimazione II, Università degli Studi di Milano.
Minerva Anestesiol. 1994 May;60(5):237-44.
To verify the applicability and the clinical significance of left ventricular wall stress determinations by intraoperative transesophageal echocardiography (TEE) during resections of abdominal aortic aneurysms.
Prospective comparison of changes in left ventricular wall stress between two groups of patients with and without coronary artery disease.
Operatory room of Universitary Institute.
Twenty-three patients with abdominal aortic aneurysms; 8 had clinically evident coronary artery disease (CAD+); 15 patients did not have clinical or electrocardiographic evidence of coronary artery disease (CAD-).
Resection of the aortic aneurysm and insertion of a synthetic prosthesis.
During operation transesophageal monitoring of left ventricular volumes and wall stress was performed during induction of anesthesia (T1), for two minutes after aortic clamping (T2), at the end of the proximal anastomosis (T3), for two minutes after aortic declamping (T4) and at the end of the procedure (T5). Circumpherential stress at end systole (sES) and end diastole (sED) was more sensitive than hemodynamic and volumetric parameters in detecting changes i function of the ischemic myocardium. In detail we observed: a significant increase of sES in CAD+versus CAD- at T2: 98 (sd 18) vs 83 (sd 14) 10(3) dyne/cm2. a significant increase of sED in CAD + versus CAD- at T2: 28.5 (sd 6) vs 22 (sd 4.5) 10(3) dyne/cm3. a similar trend of sES and sED at T4: 73 (sd 20.5) vs 46 (sd 15) 10(3) dyne/cm2 and 31 (sd 12) vs 16 (sd 7.7) 10(3) dyne/cm2 respectively. a significant increase of sED in CAD + at T5 (about 20' after T4): 26.5 (sd 9.5) vs 16 (sd 5.2) 10(3) dyne/cm2 which is expression of a persistent reduction of ventricular compliance in the ischemic patients.
Wall stress modifies MVO2 and subsequently is sensitive in detecting changes in myocardial performance. TEE could valuably integrate routine hemodynamic monitoring of patients with coronary heart disease who undergo surgical resection of abdominal aortic aneurysms.
验证术中经食管超声心动图(TEE)测定腹主动脉瘤切除术中左心室壁应力的适用性及临床意义。
对两组有和无冠状动脉疾病患者的左心室壁应力变化进行前瞻性比较。
大学研究所手术室。
23例腹主动脉瘤患者;8例有临床明显冠状动脉疾病(CAD+);15例无临床或心电图证据显示冠状动脉疾病(CAD-)。
切除主动脉瘤并植入人工合成假体。
手术期间,在麻醉诱导期(T1)、主动脉钳夹后两分钟(T2)、近端吻合结束时(T3)、主动脉松夹后两分钟(T4)及手术结束时(T5)进行经食管左心室容积和壁应力监测。收缩末期(sES)和舒张末期(sED)的圆周应力在检测缺血心肌功能变化方面比血流动力学和容积参数更敏感。具体而言,我们观察到:在T2时,CAD+组的sES显著高于CAD-组:98(标准差18)对83(标准差14)10(3)达因/平方厘米。在T2时,CAD+组的sED显著高于CAD-组:28.5(标准差6)对22(标准差4.5)10(3)达因/立方厘米。在T4时,sES和sED有相似趋势:分别为73(标准差20.5)对46(标准差15)10(3)达因/平方厘米和31(标准差12)对16(标准差7.7)10(3)达因/平方厘米。在T5(T4后约20分钟)时,CAD+组的sED显著增加:26.5(标准差9.5)对16(标准差5.2)10(3)达因/平方厘米,这表明缺血患者心室顺应性持续降低。
壁应力改变心肌耗氧量,随后在检测心肌性能变化方面很敏感。TEE可有效地补充对接受腹主动脉瘤手术切除的冠心病患者的常规血流动力学监测。