Chan A R, Johnston D H, Stoneman D
University of Toronto.
Pediatr Dent. 1994 Jul-Aug;16(4):310-3.
Neuroblastoma is an uncommon malignant neoplasm that derives from neural crest progenitor cells that normally give rise to the sympathetic nervous system. It represents 8 to 10% of all extracranial tumors in childhood. The purpose of this paper is to report a case in which a mandibular soft tissue mass was the initial presenting sign of disseminated neuroblastoma in a 2-year-old child, and to discuss the clinicopathologic features and biologic behavior of neuroblastoma.
神经母细胞瘤是一种罕见的恶性肿瘤，起源于通常会发育成交感神经系统的神经嵴祖细胞。它占儿童所有颅外肿瘤的8%至10%。本文旨在报告一例2岁儿童以下颌软组织肿块为播散性神经母细胞瘤首发体征的病例，并探讨神经母细胞瘤的临床病理特征和生物学行为。
