Vogelgesang S A, Klipple G L
Walter Reed Army Medical Center, Washington, DC.
Postgrad Med. 1994 Oct;96(5):119-22, 126-7.
Amyloidosis occurs in association with many diseases and can also be idiopathic. It is usually a systemic disease with variable presentations. The diagnosis should be suspected in patients with unexplained proteinuria, cardiomyopathy, congestive heart failure, peripheral neuropathy, carpal tunnel syndrome, macroglossia, or hepatosplenomegaly. Amyloidosis generally has a poor prognosis and responds poorly to therapy. Much needs to be learned about its pathogenesis and treatment possibilities.
淀粉样变性可与多种疾病相关联发生，也可为特发性。它通常是一种表现多样的全身性疾病。对于出现不明原因蛋白尿、心肌病、充血性心力衰竭、周围神经病变、腕管综合征、巨舌或肝脾肿大的患者，应怀疑有淀粉样变性。淀粉样变性总体预后较差，对治疗反应不佳。关于其发病机制和治疗可能性，仍有许多需要了解的地方。
