Otten T F
Probl Tuberk. 1994(3):56-9.
The paper characterizes nontuberculosis mycobacteria (NTMB) by their species, shows the structure of mycobacteriasis pathogens, drug sensibility in NTMB and the degree of their virulence for laboratory animals. The specific proportion of NTMB is Mycobacterium avium (50.8%). A total of 136 cases of mycobacterium infection were examined. As high as 20.7% of isolates from mycobacteriasis patients have been found to have a high natural resistance to most antibacterial drugs. A combination of kanamycin, ethionamide, and ethambutol is the most effective in the treatment, additionally aminoglucosides--amikacin, gentamicin, sulfamides, such as biseptol, sulfadimethoxin, as well as the quinolones ciptobay and tarivid.
该论文按物种对非结核分枝杆菌（NTMB）进行了表征，展示了分枝杆菌病病原体的结构、NTMB中的药物敏感性及其对实验动物的毒力程度。NTMB的具体占比为鸟分枝杆菌（50.8%）。共检查了136例分枝杆菌感染病例。已发现高达20.7%的分枝杆菌病患者分离株对大多数抗菌药物具有高度天然耐药性。卡那霉素、乙硫异烟胺和乙胺丁醇联合使用在治疗中最有效，此外氨基糖苷类药物——阿米卡星、庆大霉素、磺胺类药物如双嘧啶、磺胺二甲氧嘧啶，以及喹诺酮类药物环丙沙星和氧氟沙星也有效。
