Protease-activated receptors start a family.
作者信息
Coughlin S R
机构信息
Cardiovascular Research Institute, University of California, San Francisco 94143-0524.
出版信息
Proc Natl Acad Sci U S A. 1994 Sep 27;91(20):9200-2. doi: 10.1073/pnas.91.20.9200.
Abstract
摘要
相似文献
1
Protease-activated receptors start a family.蛋白酶激活受体构成了一个家族。
Proc Natl Acad Sci U S A. 1994 Sep 27;91(20):9200-2. doi: 10.1073/pnas.91.20.9200.
2
Proteinase-activated receptors: a growing family of heptahelical receptors for thrombin, trypsin and tryptase.蛋白酶激活受体：一个不断壮大的七螺旋受体家族，可被凝血酶、胰蛋白酶和类胰蛋白酶激活。
Biochem Soc Trans. 1999 Feb;27(2):246-54. doi: 10.1042/bst0270246.
3
PAQR proteins: a novel membrane receptor family defined by an ancient 7-transmembrane pass motif.PAQR蛋白：一个由古老的7次跨膜基序定义的新型膜受体家族。
J Mol Evol. 2005 Sep;61(3):372-80. doi: 10.1007/s00239-004-0375-2. Epub 2005 Jul 21.
4
Three-dimensional model for the hormone binding domains of steroid receptors.类固醇受体激素结合域的三维模型。
Proc Natl Acad Sci U S A. 1993 Nov 1;90(21):9949-53. doi: 10.1073/pnas.90.21.9949.
5
The membrane receptor for nerve growth factor.
Curr Top Microbiol Immunol. 1991;165:39-53. doi: 10.1007/978-3-642-75747-1_3.
6
The RACK1 scaffold protein: a dynamic cog in cell response mechanisms.RACK1支架蛋白：细胞应答机制中的一个动态齿轮
Mol Pharmacol. 2002 Dec;62(6):1261-73. doi: 10.1124/mol.62.6.1261.
7
CD164.
J Biol Regul Homeost Agents. 2001 Oct-Dec;15(4):394-6.
8
Evidence for new homotypic and heterotypic interactions between transmembrane helices of proteins involved in receptor tyrosine kinase and neuropilin signaling.参与受体酪氨酸激酶和神经纤毛蛋白信号传导的蛋白质跨膜螺旋之间新的同型和异型相互作用的证据。
J Mol Biol. 2014 Dec 12;426(24):4099-4111. doi: 10.1016/j.jmb.2014.10.007. Epub 2014 Oct 12.
9
Protease-activated receptors.
Curr Top Dev Biol. 2003;54:343-69. doi: 10.1016/s0070-2153(03)54014-5.
10
Sequence and expression pattern of a novel human orphan G-protein-coupled receptor, GPRC5B, a family C receptor with a short amino-terminal domain.一种新型人类孤儿G蛋白偶联受体GPRC5B的序列和表达模式，GPRC5B是一种具有短氨基末端结构域的C族受体。
Genomics. 2000 Apr 15;65(2):121-8. doi: 10.1006/geno.2000.6164.
引用本文的文献
1
The protease-activated receptors are expressed in glioblastoma and differentially modulate adherent versus stem-like growth of LN-18 GBM cells.蛋白酶激活受体在胶质母细胞瘤中表达，并对LN - 18胶质母细胞瘤细胞的贴壁生长与干细胞样生长进行差异性调节。
Front Oncol. 2025 Jul 22;15:1582996. doi: 10.3389/fonc.2025.1582996. eCollection 2025.
2
Thrombin induces morphological and inflammatory astrocytic responses via activation of PAR1 receptor.凝血酶通过激活PAR1受体诱导星形胶质细胞发生形态学和炎症反应。
Cell Death Discov. 2022 Apr 11;8(1):189. doi: 10.1038/s41420-022-00997-4.
3
Are apolipoprotein E fragments a promising new therapeutic target for Alzheimer's disease?载脂蛋白E片段会是阿尔茨海默病一个有前景的新治疗靶点吗？
Ther Adv Chronic Dis. 2022 Mar 17;13:20406223221081605. doi: 10.1177/20406223221081605. eCollection 2022.
4
Modulation of Intestinal Epithelial Permeability via Protease-Activated Receptor-2-Induced Autophagy.通过蛋白酶激活受体 2 诱导的自噬调节肠道上皮通透性。
Cells. 2022 Mar 3;11(5):878. doi: 10.3390/cells11050878.
5
Complement and Coagulation System Crosstalk in Synaptic and Neural Conduction in the Central and Peripheral Nervous Systems.中枢和外周神经系统中补体与凝血系统在突触和神经传导中的相互作用
Biomedicines. 2021 Dec 20;9(12):1950. doi: 10.3390/biomedicines9121950.
6
An Insight into GPCR and G-Proteins as Cancer Drivers.G 蛋白偶联受体（GPCR）和 G 蛋白作为癌症驱动因素的深入了解。
Cells. 2021 Nov 24;10(12):3288. doi: 10.3390/cells10123288.
7
A rapid fluorogenic GPCR-β-arrestin interaction assay.一种快速荧光 GPCR-β-arrestin 相互作用检测法。
Protein Sci. 2018 Apr;27(4):874-879. doi: 10.1002/pro.3385. Epub 2018 Feb 23.
8
G Protein-Coupled Receptors in Cancer.癌症中的G蛋白偶联受体
Int J Mol Sci. 2016 Aug 12;17(8):1320. doi: 10.3390/ijms17081320.
9
The Importance of Thrombin in Cerebral Injury and Disease.凝血酶在脑损伤和疾病中的重要性。
Int J Mol Sci. 2016 Jan 11;17(1):84. doi: 10.3390/ijms17010084.
10
Increased expression of cathelicidin by direct activation of protease-activated receptor 2: possible implications on the pathogenesis of rosacea.通过直接激活蛋白酶激活受体2增加抗菌肽的表达：对酒渣鼻发病机制的可能影响。
Yonsei Med J. 2014 Nov;55(6):1648-55. doi: 10.3349/ymj.2014.55.6.1648.
本文引用的文献
1
Response of blood leukocytes to thrombin receptor peptides.血液白细胞对凝血酶受体肽的反应。
J Leukoc Biol. 1993 Aug;54(2):145-51. doi: 10.1002/jlb.54.2.145.
2
The thrombin receptor extracellular domain contains sites crucial for peptide ligand-induced activation.凝血酶受体胞外结构域包含对肽配体诱导激活至关重要的位点。
J Clin Invest. 1993 Apr;91(4):1405-13. doi: 10.1172/JCI116344.
3
Thrombin stimulates proliferation of cultured rat aortic smooth muscle cells by a proteolytically activated receptor.凝血酶通过蛋白水解激活受体刺激培养的大鼠主动脉平滑肌细胞增殖。
J Clin Invest. 1993 Jan;91(1):94-8. doi: 10.1172/JCI116206.
4
5
Specificity of the thrombin receptor for agonist peptide is defined by its extracellular surface.凝血酶受体对激动剂肽的特异性由其细胞外表面决定。
Nature. 1994 Apr 14;368(6472):648-51. doi: 10.1038/368648a0.
6
Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes.凝血酶与凝血酶受体肽复合物的晶体结构：预期及新结合模式的存在
Biochemistry. 1994 Mar 22;33(11):3266-79. doi: 10.1021/bi00177a018.
7
A matrix metalloproteinase expressed on the surface of invasive tumour cells.一种在侵袭性肿瘤细胞表面表达的基质金属蛋白酶。
Nature. 1994 Jul 7;370(6484):61-5. doi: 10.1038/370061a0.
8
Molecular cloning of a potential proteinase activated receptor.
Proc Natl Acad Sci U S A. 1994 Sep 27;91(20):9208-12. doi: 10.1073/pnas.91.20.9208.
9
Kinetics of thrombin receptor cleavage on intact cells. Relation to signaling.
J Biol Chem. 1993 May 5;268(13):9780-6.
10
The structure of a complex of recombinant hirudin and human alpha-thrombin.重组水蛭素与人α-凝血酶复合物的结构
Science. 1990 Jul 20;249(4966):277-80. doi: 10.1126/science.2374926.
Zotero 插件