Pascoe P A
Royal Air Force Institute of Aviation Medicine, Farnborough, Hampshire, U.K.
Pharmacol Ther. 1994;61(1-2):227-36. doi: 10.1016/0163-7258(94)90064-7.
The circadian cycle of sleep and wakefulness in humans is controlled by the activity of many neurotransmitters. Studies of the effects of drugs on the central nervous system have elucidated some of the mechanisms that may be involved. Some transmitters are concerned with the basic control of sleep and wakefulness, influencing both alertness during the day and the pattern of nocturnal sleep. On the other hand, there are other transmitters that appear to be concerned primarily with the manifestation of wakefulness and vigilance, without a direct role in the process of sleep.
人类睡眠与清醒的昼夜节律由多种神经递质的活动控制。对药物对中枢神经系统影响的研究阐明了一些可能涉及的机制。一些递质与睡眠和清醒的基本控制有关，影响白天的警觉性和夜间睡眠模式。另一方面，还有其他一些递质似乎主要与清醒和警觉的表现有关，在睡眠过程中没有直接作用。
