Yahr P, Finn P D, Hoffman N W, Sayag N
Department of Psychobiology, University of California, Irvine 92717-4550.
Psychoneuroendocrinology. 1994;19(5-7):463-70. doi: 10.1016/0306-4530(94)90033-7.
The research summarized here shows that the two major cell groups of the sexually dimorphic area (SDA) of the gerbil hypothalamus are essential for male sex behavior. Bilateral cell-body lesions of either the medial or lateral SDA virtually eliminate mating in sexually experienced male gerbils given exogenous testosterone. Similar deficits occur when the SDA is bilaterally disconnected from the retrorubral field (RRF) as a result of unilateral cell-body lesions in the SDA and contralateral RRF. The A8 cells of the RRF do not account for this effect. Bilaterally disconnecting the SDA from the caudomedial part of the bed nucleus of the stria terminalis (caudal BSTm) also eliminates sexual activity. Disconnecting the SDA from the medial amygdala does not mimic this effect. Neither does disconnecting the medial amygdala from the caudal BSTm. Thus, caudal BSTm neurons that are essential for mating via connections with the SDA do not simply relay information from the medial amygdala.
此处总结的研究表明，沙鼠下丘脑性二态区（SDA）的两个主要细胞群对雄性性行为至关重要。给予外源性睾酮后，内侧或外侧SDA的双侧细胞体损伤实际上会消除有性经验的雄性沙鼠的交配行为。当由于SDA和对侧红核后区（RRF）的单侧细胞体损伤导致SDA与RRF双侧断开连接时，也会出现类似的缺陷。RRF的A8细胞对此效应无影响。将SDA与终纹床核的尾内侧部分（尾侧BSTm）双侧断开连接也会消除性活动。将SDA与内侧杏仁核断开连接不会模拟这种效应。将内侧杏仁核与尾侧BSTm断开连接也不会。因此，通过与SDA的连接对交配至关重要的尾侧BSTm神经元并非简单地中继来自内侧杏仁核的信息。
