Mornex F, Favaudon V, Mazeron J J
Département de radiothérapie, Centre Léon-Bérard, Lyon.
Rev Prat. 1994 Apr 15;44(8):1003-10.
Mechanisms of death following irradiation of malignant cells are incompletely understood. Radiation-induced lesions and their consequences on the cancer cell are described. Factors conditioning malignant cell response to radiation are discussed, as well as the mechanisms of radiation-induced carcinogenesis. Finally, the recent molecular biology contributions to gene regulation during cell growth are presented.
恶性细胞受辐射后的死亡机制尚未完全明确。文中描述了辐射诱导的损伤及其对癌细胞的影响。讨论了影响恶性细胞对辐射反应的因素以及辐射致癌的机制。最后,介绍了细胞生长过程中基因调控方面最新的分子生物学研究成果。